Journal: Kidney international
Article Title: Early treatment with cGMP phosphodiesterase inhibitor ameliorates progression of renal damage.
doi: 10.1111/j.1523-1755.2005.00669.x
Figure Lengend Snippet: Fig. 6. Staining with panendothelial monoclonal antibody (RECA-1) expressed as the ratio of positive area/total area in glomeruli (A) and tubulointerstitial regions (B). Renal ablation [5/6 nephrectomy (5/6 Nx)] reduces and the treatment with sildenafil (5/6 Nx.SIL) prevents the loss of glomerular and peritubular capillaries. ∗P < 0.05; ∗∗∗P < 0.001. Representative microphotographs of renal sections of a vehicle-treated rat (5/6 nephrectomy group) (C) and a sildenafil-treated rat (D) (immunoperoxidase staining).
Article Snippet: Glomerular and peritubular capillaries were identified with panendothelial monoclonal mouse antirat RECA-1 antibody (clone HIS52) (Serotec Inc., Raleigh, NC, USA).
Techniques: Staining, Immunoperoxidase Staining